{"id":1168,"date":"2025-03-10T14:31:28","date_gmt":"2025-03-10T14:31:28","guid":{"rendered":"https:\/\/urolistic.com\/?p=1168"},"modified":"2025-05-27T08:07:10","modified_gmt":"2025-05-27T08:07:10","slug":"introduccion-a-los-toxicos","status":"publish","type":"post","link":"https:\/\/urolistic.com\/fr\/blog\/2025\/03\/10\/introduccion-a-los-toxicos\/","title":{"rendered":"Introduction aux produits toxiques"},"content":{"rendered":"
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Le monde des substances toxiques et leur relation avec notre sant\u00e9 est vaste et complexe. L'homme a v\u00e9cu pendant des millions d'ann\u00e9es sur une plan\u00e8te non pollu\u00e9e, o\u00f9 les seules toxines auxquelles il \u00e9tait expos\u00e9 \u00e9taient des toxines naturelles, comme la consommation de certaines plantes ou animaux v\u00e9n\u00e9neux, ou leur agression (morsures, frottement de plantes sur la peau). \u00c0 ces toxines externes s'ajoutaient des toxines internes, celles produites par notre propre m\u00e9tabolisme sous forme de d\u00e9chets que notre corps doit \u00e9liminer, ou celles produites par notre microbiote, principalement au niveau intestinal. Ainsi, pendant des ann\u00e9es, notre organisme a pu g\u00e9rer correctement l'exposition \u00e0 ces toxines famili\u00e8res, l'\u00e9volution au cours de mill\u00e9naires et de mill\u00e9naires lui ayant permis de s'adapter.\u00a0<\/p>\n\n

\u00a0\u00a0\u00a0\u00a0\u00a0La d\u00e9sintoxication a lieu principalement la nuit, gr\u00e2ce au fonctionnement du foie. Un bon repos nocturne est donc essentiel pour \u00e9liminer les substances nocives. Cette d\u00e9toxification s'effectue par le biais de certains m\u00e9canismes biochimiques qui permettent aux substances toxiques de devenir plus hydrosolubles et d'\u00eatre ensuite \u00e9limin\u00e9es par les reins dans l'urine, ou plus liposolubles et d'\u00eatre \u00e9limin\u00e9es par la bile dans les selles. Cette transformation h\u00e9patique des toxines se fait en deux phases, la phase I et la phase II de conjugaison. Mais que se passe-t-il si notre organisme est soudainement expos\u00e9 \u00e0 des milliers de nouvelles substances toxiques qu'il ne sait pas comment traiter ? Il est fort probable que les m\u00e9canismes de d\u00e9toxification soient d\u00e9bord\u00e9s. C'est exactement ce qui s'est pass\u00e9 ces derni\u00e8res ann\u00e9es.\u00a0<\/p>\n\n

\u00a0\u00a0\u00a0\u00a0\u00a0Le probl\u00e8me a commenc\u00e9 avec la r\u00e9volution industrielle, mais s'est \u00e9tendu \u00e0 grande \u00e9chelle avec le d\u00e9veloppement de l'industrie p\u00e9troli\u00e8re et chimique au 20\u00e8me si\u00e8cle. Depuis, notre plan\u00e8te et notre corps sont de plus en plus envahis par de nombreuses substances qui perturbent leur fonctionnement. Lorsque les m\u00e9canismes de d\u00e9toxification sont satur\u00e9s, les toxines s'accumulent dans l'organisme. Ces substances accumul\u00e9es vont \u00eatre stock\u00e9es principalement dans le tissu adipeux et le cerveau, elles vont provoquer des inflammations \u00e0 ce niveau et des dysfonctionnements de diff\u00e9rents organes, elles vont mimer ou bloquer l'action de certaines hormones ou encore produire des alt\u00e9rations au niveau du syst\u00e8me immunitaire. De plus, comme je l'ai d\u00e9j\u00e0 expliqu\u00e9, de nombreuses toxines sont \u00e9limin\u00e9es dans les selles ou les urines, raison de plus pour les consid\u00e9rer comme dangereuses pour notre vessie, en plus de l'implication indirecte qu'elles peuvent avoir dans les dysfonctionnements de cet organe par leur effet sur le syst\u00e8me nerveux ou endocrinien.\u00a0<\/p>\n\n

\u00a0\u00a0\u00a0\u00a0\u00a0Les m\u00e9canismes d'action des toxines dans notre organisme sont nombreux. Je ne peux pas d\u00e9crire chacun d'entre eux sur ce texte, mais dans les articles suivants, j\u2019\u00e9noncerai bri\u00e8vement comment certains d'entre eux agissent dans notre syst\u00e8me urinaire, favorisant le d\u00e9veloppement de pathologies et, surtout, d'infections ou d'inflammations.<\/p>\n\n

Alcool et tabac<\/h3>\n\n

\u00a0\u00a0\u00a0\u00a0\u00a0L'effet n\u00e9faste de ces deux toxines sur notre sant\u00e9 est bien connu. On sait qu'elles sont la cause directe de nombreux cancers, notamment les cancers urologiques de la vessie et du rein, et qu'elles alt\u00e8rent la paroi de la vessie et le microbiote, y compris le microbiote urinaire. Dans le cas de la vessie, ce point est controvers\u00e9. Plusieurs \u00e9tudes ont analys\u00e9 le microbiote urinaire de fumeurs avec et sans cancer de la vessie et y ont trouv\u00e9 des compositions diff\u00e9rentes, tandis qu'une autre \u00e9tude a analys\u00e9 le microbiote de patients avec un cancer de la vessie, fumeurs et non-fumeurs, et n'a pas trouv\u00e9 de diff\u00e9rences significatives. Le tabac et l'alcool alt\u00e8rent \u00e9galement l'immunit\u00e9, nous font consommer des vitamines et des oligo-\u00e9l\u00e9ments en augmentant nos besoins, et diminuent le pouvoir antioxydant et d\u00e9toxifiant du foie. Ainsi, directement ou indirectement, ces deux substances finissent par avoir un effet sur notre susceptibilit\u00e9 aux infections, bien qu'il n'y ait pas d'\u00e9tudes publi\u00e9es \u00e9tablissant un lien direct entre ces substances toxiques et les infections urinaires \u00e0 r\u00e9p\u00e9tition.<\/p>\n\n

Bibliographie :<\/em><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Olea N (2019).\u00a0Lib\u00e9rate de t\u00f3xicos.<\/em>\u00a0RBA libros.<\/p>\n

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Mobley D, Baum N. Smoking: Its Impact on Urologic Health. Rev Urol. 2015;17(4):220-5.\u00a0<\/p>\n

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Zhu H, Zhan X, Wang C, Deng Y, Li X, et al. Causal Associations Between Tobacco, Alcohol Use and Risk of Infectious Diseases: A Mendelian Randomization Study. Infect Dis Ther. 2023 Mar;12(3):965-977.\u00a0<\/p>\n

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Atawodi SE, Richter E. Bacterial reduction of N-oxides of tobacco-specific nitrosamines (TSNA). Hum Exp Toxicol. 1996 Apr;15(4):329-34.<\/p>\n

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Ma W, Zhang W, Shen L, Liu J, Yang F, et al. Can Smoking Cause Differences in Urine Microbiome in Male Patients With Bladder Cancer? A Retrospective Study. Front Oncol. 2021 Jun 8;11:677605.\u00a0<\/p>\n

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Moynihan M, Sullivan T, Provenzano K, Rieger-Christ K. Urinary Microbiome Evaluation in Patients Presenting with Hematuria with a Focus on Exposure to Tobacco Smoke. Res Rep Urol. 2019 Dec 27;11:359-367.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Le monde des substances toxiques et leur relation avec notre sant\u00e9 est vaste et complexe. L'homme vit depuis des millions d'ann\u00e9es dans un environnement o\u00f9 il n'y a pas d'autre solution que d'utiliser des produits toxiques. [...]<\/span><\/p>","protected":false},"author":1,"featured_media":1185,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"class_list":["post-1168","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-toxicos"],"yoast_head":"\nIntroducci\u00f3n a los t\u00f3xicos | Urolistic<\/title>\n<meta name=\"description\" content=\"Redescubre el bienestar con Urolistic, el proyecto de la Dra. 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