{"id":1482,"date":"2025-05-26T10:12:14","date_gmt":"2025-05-26T10:12:14","guid":{"rendered":"https:\/\/urolistic.com\/?p=1482"},"modified":"2025-05-27T08:04:41","modified_gmt":"2025-05-27T08:04:41","slug":"el-sistema-inmunitario-y-la-microbiota-intestinal","status":"publish","type":"post","link":"https:\/\/urolistic.com\/fr\/blog\/2025\/05\/26\/el-sistema-inmunitario-y-la-microbiota-intestinal\/","title":{"rendered":"Le syst\u00e8me immunitaire et le microbiote intestinal"},"content":{"rendered":"
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L'intestin est dot\u00e9 d'un syst\u00e8me immunitaire tr\u00e8s puissant et sp\u00e9cialis\u00e9. On pense qu'environ 80% des cellules immunitaires de notre corps y r\u00e9sident. Cela peut sembler exag\u00e9r\u00e9, mais il est important de comprendre pourquoi. Le tube digestif est l'une des barri\u00e8res qui s\u00e9parent notre corps du monde ext\u00e9rieur, avec les poumons, la peau et d'autres muqueuses telles que les muqueuses buccale et vaginale. De toutes ces barri\u00e8res, c'est celle qui pr\u00e9sente la plus grande surface. Classiquement, on dit qu'elle mesure environ 250 \u00e0 300 m2<\/sup>\u00a0de surface d'\u00e9change, soit la taille d'un court de tennis. Cependant, des publications r\u00e9centes parlent d'une surface plus petite, mais n\u00e9anmoins tr\u00e8s importante, d'environ 32 m2<\/sup>, l'\u00e9quivalent d'un demi-terrain de badminton. On peut donc le consid\u00e9rer comme le principal \"poste de douane\" de notre corps. Chaque jour, des millions de substances (mol\u00e9cules alimentaires, micro-organismes, toxines, etc.) arrivent dans l'intestin, et cet organe doit d\u00e9cider pour chacune d'entre elles de les laisser passer ou pas dans l'organisme. Pour ce faire, outre la fonction des ent\u00e9rocytes (les cellules qui tapissent la paroi intestinale), il est aid\u00e9 par le syst\u00e8me immunitaire, qui joue le r\u00f4le de de gendarme douanier et demande le \"passeport\" \u00e0 chacune de ces substances .<\/p>\n\n

Bibliographie :<\/em><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Arponen S (2021). Es la microbiota, idiota. Alienta.<\/p>\n

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Maynard CL, Elson CO, Hatton RD, Weaver CT. Reciprocal interactions of the intestinal microbiota and immune system. Nature. 2012 Sep 13;489(7415):231-41.<\/p>\n

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Cryan JF, O\u2019Riordan KJ, Cowan CSM, Sandhu KV, Bastiaanssen TFS, et al. The Microbiota-Gut-Brain Axis. Physiol Rev. 2019 Oct 1;99(4):1877-2013.\u00a0<\/p>\n

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Takiishi T, Fenero CIM, C\u00e2mara NOS. Intestinal barrier and gut microbiota: Shaping our immune responses throughout life. Tissue Barriers. 2017 Oct 2;5(4)<\/p>\n

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Martin-Gallausiaux C, Marinelli L, Blottiere HH, Larraufie P, Lapaque N. Short Chain Fatty Acids \u2013 mechanisms and functional importance in the gut.\u00a0Proceedings of the Nutrition Society, 2021, 80 (1), pp. 37-49.<\/p>\n

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Helander HF, F\u00e4ndriks L. Surface area of the digestive tract \u2013 revisited. Scand J Gastroenterol. 2014 Jun;49(6):681-9.<\/p>\n

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Maynard CL, Elson CO, Hatton RD, Weaver CT. Reciprocal interactions of the intestinal microbiota and immune system. Nature. 2012 Sep 13;489(7415):231-41.<\/p>\n

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Cryan JF, O\u2019Riordan KJ, Cowan CSM, Sandhu KV, Bastiaanssen TFS, et al. The Microbiota-Gut-Brain Axis. Physiol Rev. 2019 Oct 1;99(4):1877-2013.\u00a0<\/p>\n

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Takiishi T, Fenero CIM, C\u00e2mara NOS. Intestinal barrier and gut microbiota: Shaping our immune responses throughout life. Tissue Barriers. 2017 Oct 2;5(4).<\/p>\n

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Mitchell NM, Johnson JR, Johnston B, Curtiss R 3rd, Mellata M. Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs. Appl Environ Microbiol. 2015 Feb;81(3):1177-87.<\/p>\n

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Buberg ML, Mo SS, Sekse C, Sunde M, Wasteson Y, Wits\u00f8 IL. Population structure and uropathogenic potential of extended-spectrum cephalosporin-resistant Escherichia coli from retail chicken meat. BMC Microbiol. 2021 Mar 29;21(1):94.<\/p>\n

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Magruder M, Sholi AN, Gong C, et al. Gut uropathogen abundance is a risk factor for development of bacteriuria and urinary tract infection.\u00a0Nat Commun. 2019;10(1):5521.\u00a0<\/p>\n

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Magruder M, Edusei E, Zhang L, et al. Gut commensal microbiota and decreased risk for\u00a0Enterobacteriaceae\u00a0bacteriuria and urinary tract infection.\u00a0Gut Microbes. 2020;12(1):1805281.\u00a0<\/p>\n

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Spaulding CN, Klein RD, Ruer S, et al. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.\u00a0Nature. 2017;546(7659):528-532.\u00a0<\/p>\n

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Jones-Freeman B, Chonwerawong M, Marcelino VR, Deshpande AV, Forster SC, Starkey MR. The microbiome and host mucosal interactions in urinary tract diseases. Mucosal Immunol. 2021 Jul;14(4):779-792.\u00a0<\/p>\n

<\/p>\n

Mitchell NM, Johnson JR, Johnston B, Curtiss R 3rd, Mellata M. Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs. Appl Environ Microbiol. 2015 Feb;81(3):1177-87.<\/p>\n

<\/p>\n

Buberg ML, Mo SS, Sekse C, Sunde M, Wasteson Y, Wits\u00f8 IL. Population structure and uropathogenic potential of extended-spectrum cephalosporin-resistant Escherichia coli from retail chicken meat. BMC Microbiol. 2021 Mar 29;21(1):94.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

L'intestin est dot\u00e9 d'un syst\u00e8me immunitaire tr\u00e8s puissant et sp\u00e9cialis\u00e9. On pense qu'environ 80% des cellules immunitaires de notre corps y r\u00e9sident. [...]<\/span><\/p>","protected":false},"author":1,"featured_media":1516,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"class_list":["post-1482","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-microbiota"],"yoast_head":"\nEl sistema inmunitario y la\u00a0microbiota intestinal | Urolistic<\/title>\n<meta name=\"description\" content=\"Redescubre el bienestar con Urolistic, el proyecto de la Dra. 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